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Platelets Increase the Expression of PD-L1 in Ovarian Cancer

SIMPLE SUMMARY: One-third of patients with ovarian cancer have elevated platelet counts associated with a poor prognosis. We found that platelets increase the expression of immune checkpoint (PD-L1) in ovarian cancer in mice and patients. Reducing platelet counts or inhibiting platelet function redu...

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Detalles Bibliográficos
Autores principales: Cho, Min Soon, Lee, Hani, Gonzalez-Delgado, Ricardo, Li, Dan, Sasano, Tomoyuki, Carlos-Alcalde, Wendolyn, Ma, Qing, Liu, Jinsong, Sood, Anil K., Afshar-Kharghan, Vahid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139585/
https://www.ncbi.nlm.nih.gov/pubmed/35626102
http://dx.doi.org/10.3390/cancers14102498