Distinct Effector Programs of Brain-Homing CD8(+) T Cells in Multiple Sclerosis

The effector programs of CD8(+) memory T cells are influenced by the transcription factors RUNX3, EOMES and T-bet. How these factors define brain-homing CD8(+) memory T cells in multiple sclerosis (MS) remains unknown. To address this, we analyzed blood, CSF and brain tissues from MS patients for th...

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Detalles Bibliográficos
Autores principales: Koetzier, Steven C., van Langelaar, Jamie, Melief, Marie-José, Wierenga-Wolf, Annet F., Corsten, Cato E. A., Blok, Katelijn M., Hoeks, Cindy, Broux, Bieke, Wokke, Beatrijs, van Luijn, Marvin M., Smolders, Joost
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139595/
https://www.ncbi.nlm.nih.gov/pubmed/35626671
http://dx.doi.org/10.3390/cells11101634

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139595/
https://www.ncbi.nlm.nih.gov/pubmed/35626671
http://dx.doi.org/10.3390/cells11101634

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