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p62 Promotes Survival and Hepatocarcinogenesis in Mice with Liver-Specific NEMO Ablation
SIMPLE SUMMARY: Chronic liver injury is a predisposing factor for hepatocellular carcinoma (HCC) development. p62-mediated Nrf2 overactivation has been shown to drive liver injury and HCC in mice with hepatic impairment of autophagy. Here, we addressed the role of this pathway in a liver disease mou...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139637/ https://www.ncbi.nlm.nih.gov/pubmed/35626041 http://dx.doi.org/10.3390/cancers14102436 |