P720R USP8 Mutation Is Associated with a Better Responsiveness to Pasireotide in ACTH-Secreting PitNETs

SIMPLE SUMMARY: Somatic mutations in USP8 gene have been identified in 11–60% of patients with ACTH-secreting pituitary tumors. This study investigated the impact of USP8 mutations on corticotroph tumor cells responsiveness to the treatment with the somatostatin analog pasireotide. Although we found...

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Detalles Bibliográficos
Autores principales: Treppiedi, Donatella, Marra, Giusy, Di Muro, Genesio, Esposito, Emanuela, Barbieri, Anna Maria, Catalano, Rosa, Mangili, Federica, Bravi, Francesca, Locatelli, Marco, Lania, Andrea Gerardo, Ferrante, Emanuele, Indirli, Rita, Nozza, Emma, Arlati, Federico, Spada, Anna, Arosio, Maura, Mantovani, Giovanna, Peverelli, Erika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139692/
https://www.ncbi.nlm.nih.gov/pubmed/35626057
http://dx.doi.org/10.3390/cancers14102455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139692/
https://www.ncbi.nlm.nih.gov/pubmed/35626057
http://dx.doi.org/10.3390/cancers14102455

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