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Toxoplasma gondii Rhoptry Protein 7 (ROP7) Interacts with NLRP3 and Promotes Inflammasome Hyperactivation in THP-1-Derived Macrophages

Toxoplasma gondii is a common opportunistic protozoan pathogen that can parasitize the karyocytes of humans and virtually all other warm-blooded animals. In the host’s innate immune response to T. gondii infection, inflammasomes can mediate the maturation of pro-IL-1β and pro-IL-18, which further en...

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Detalles Bibliográficos
Autores principales: Zhu, Lijun, Qi, Wanjun, Yang, Guang, Yang, Yurong, Wang, Yuwen, Zheng, Lulu, Fu, Yongfeng, Cheng, Xunjia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139738/
https://www.ncbi.nlm.nih.gov/pubmed/35626667
http://dx.doi.org/10.3390/cells11101630