Reverting TP53 Mutation in Breast Cancer Cells: Prime Editing Workflow and Technical Considerations

Breast cancer is the leading cause of cancer-related deaths in women. The aggressive breast cancer subtype is commonly linked to the genetic alterations in the TP53 tumor suppressor gene, predominantly the missense mutations. Robust experimental models are needed to gain better insights into these m...

Descripción completa

Detalles Bibliográficos
Autores principales: Abuhamad, Asmaa Y., Mohamad Zamberi, Nurul Nadia, Sheen, Ling, Naes, Safaa M., Mohd Yusuf, Siti Nur Hasanah, Ahmad Tajudin, Asilah, Mohtar, M. Aiman, Amir Hamzah, Amir Syahir, Syafruddin, Saiful Effendi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139850/
https://www.ncbi.nlm.nih.gov/pubmed/35626649
http://dx.doi.org/10.3390/cells11101612

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139850/
https://www.ncbi.nlm.nih.gov/pubmed/35626649
http://dx.doi.org/10.3390/cells11101612

Ejemplares similares