Clinical Landscape of PARP Inhibitors in Ovarian Cancer: Molecular Mechanisms and Clues to Overcome Resistance

SIMPLE SUMMARY: Recent development of maintenance therapy using PARP inhibitors in ovarian cancer has led to a significant improvement in survival rates. However, resistance to these inhibitors can occur in patients, causing disease progression or relapse. Consequently, novel treatment strategies ar...

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Detalles Bibliográficos
Autores principales: Kyo, Satoru, Kanno, Kosuke, Takakura, Masahiro, Yamashita, Hitomi, Ishikawa, Masako, Ishibashi, Tomoka, Sato, Seiya, Nakayama, Kentaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139943/
https://www.ncbi.nlm.nih.gov/pubmed/35626108
http://dx.doi.org/10.3390/cancers14102504

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139943/
https://www.ncbi.nlm.nih.gov/pubmed/35626108
http://dx.doi.org/10.3390/cancers14102504

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