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Clinical Landscape of PARP Inhibitors in Ovarian Cancer: Molecular Mechanisms and Clues to Overcome Resistance

SIMPLE SUMMARY: Recent development of maintenance therapy using PARP inhibitors in ovarian cancer has led to a significant improvement in survival rates. However, resistance to these inhibitors can occur in patients, causing disease progression or relapse. Consequently, novel treatment strategies ar...

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Detalles Bibliográficos
Autores principales:	Kyo, Satoru, Kanno, Kosuke, Takakura, Masahiro, Yamashita, Hitomi, Ishikawa, Masako, Ishibashi, Tomoka, Sato, Seiya, Nakayama, Kentaro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139943/ https://www.ncbi.nlm.nih.gov/pubmed/35626108 http://dx.doi.org/10.3390/cancers14102504

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