Hepatocyte Thorns, A Novel Drug-Induced Stress Response in Human and Mouse Liver Spheroids

The in vivo-relevant phenotype of 3D liver spheroids allows for long-term studies of, e.g., novel mechanisms of chronic drug-induced liver toxicity. Using this system, we present a novel drug-induced stress response in human and murine hepatocyte spheroids, wherein long slender filaments form after...

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Detalles Bibliográficos
Autores principales: Pridgeon, Chris S., Bolhuis, Dian P., Milosavljević, Filip, Manojlović, Marina, Végvári, Ákos, Gaetani, Massimiliano, Jukić, Marin M., Ingelman-Sundberg, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139950/
https://www.ncbi.nlm.nih.gov/pubmed/35626634
http://dx.doi.org/10.3390/cells11101597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139950/
https://www.ncbi.nlm.nih.gov/pubmed/35626634
http://dx.doi.org/10.3390/cells11101597

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