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Acquired αSMA Expression in Pericytes Coincides with Aberrant Vascular Structure and Function in Pancreatic Ductal Adenocarcinoma

SIMPLE SUMMARY: The pancreatic cancer field suffers from a lack of effective treatment options in part due to the severely compromised tumor vasculature that leads to hypoxia and an immunosuppressive environment. Our study aimed to identify and characterize pathological pericyte phenotypes that cont...

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Detalles Bibliográficos
Autores principales: Natarajan, Vikneshwari, Ha, Sangdeuk, Delgado, Alexander, Jacobson, Reed, Alhalhooly, Lina, Choi, Yongki, Kim, Jiha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139959/
https://www.ncbi.nlm.nih.gov/pubmed/35626052
http://dx.doi.org/10.3390/cancers14102448