IRE1α Inhibitors as a Promising Therapeutic Strategy in Blood Malignancies

SIMPLE SUMMARY: Blood malignancies account for 6.9% of all cancer deaths. Inositol-requiring enzyme 1 alpha (IRE1α), a part of the unfolded protein response (UPR), has been shown to be pivotal for cancer cell development and progression, including blood cancers. Furthermore, IRE1α levels are often e...

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Detalles Bibliográficos
Autores principales: Wiese, Wojciech, Siwecka, Natalia, Wawrzynkiewicz, Adam, Rozpędek-Kamińska, Wioletta, Kucharska, Ewa, Majsterek, Ireneusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139960/
https://www.ncbi.nlm.nih.gov/pubmed/35626128
http://dx.doi.org/10.3390/cancers14102526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139960/
https://www.ncbi.nlm.nih.gov/pubmed/35626128
http://dx.doi.org/10.3390/cancers14102526

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