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IRE1α Inhibitors as a Promising Therapeutic Strategy in Blood Malignancies
SIMPLE SUMMARY: Blood malignancies account for 6.9% of all cancer deaths. Inositol-requiring enzyme 1 alpha (IRE1α), a part of the unfolded protein response (UPR), has been shown to be pivotal for cancer cell development and progression, including blood cancers. Furthermore, IRE1α levels are often e...
Autores principales: | Wiese, Wojciech, Siwecka, Natalia, Wawrzynkiewicz, Adam, Rozpędek-Kamińska, Wioletta, Kucharska, Ewa, Majsterek, Ireneusz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139960/ https://www.ncbi.nlm.nih.gov/pubmed/35626128 http://dx.doi.org/10.3390/cancers14102526 |
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