Chromosomal Instability in Chronic Myeloid Leukemia: Mechanistic Insights and Effects

SIMPLE SUMMARY: Chronic myeloid leukemia is a disease diagnosed by the presence of the Philadelphia chromosome, which leads to the BCR::ABL fusion oncoprotein and overactive tyrosine kinase activity. Multiple other genetic aberrations and chromosomal changes make the disease very heterogeneous, and...

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Detalles Bibliográficos
Autores principales: Senapati, Jayastu, Sasaki, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140097/
https://www.ncbi.nlm.nih.gov/pubmed/35626137
http://dx.doi.org/10.3390/cancers14102533

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140097/
https://www.ncbi.nlm.nih.gov/pubmed/35626137
http://dx.doi.org/10.3390/cancers14102533

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