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Chromosomal Instability in Chronic Myeloid Leukemia: Mechanistic Insights and Effects
SIMPLE SUMMARY: Chronic myeloid leukemia is a disease diagnosed by the presence of the Philadelphia chromosome, which leads to the BCR::ABL fusion oncoprotein and overactive tyrosine kinase activity. Multiple other genetic aberrations and chromosomal changes make the disease very heterogeneous, and...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140097/ https://www.ncbi.nlm.nih.gov/pubmed/35626137 http://dx.doi.org/10.3390/cancers14102533 |