SMER28 Attenuates PI3K/mTOR Signaling by Direct Inhibition of PI3K p110 Delta

SMER28 (Small molecule enhancer of Rapamycin 28) is an autophagy-inducing compound functioning by a hitherto unknown mechanism. Here, we confirm its autophagy-inducing effect by assessing classical autophagy-related parameters. Interestingly, we also discovered several additional effects of SMER28,...

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Detalles Bibliográficos
Autores principales: Kirchenwitz, Marco, Stahnke, Stephanie, Prettin, Silvia, Borowiak, Malgorzata, Menke, Laura, Sieben, Christian, Birchmeier, Carmen, Rottner, Klemens, Stradal, Theresia E. B., Steffen, Anika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140127/
https://www.ncbi.nlm.nih.gov/pubmed/35626685
http://dx.doi.org/10.3390/cells11101648

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140127/
https://www.ncbi.nlm.nih.gov/pubmed/35626685
http://dx.doi.org/10.3390/cells11101648

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