Cargando…

Role of yUbp8 in Mitochondria and Hypoxia Entangles the Finding of Human Ortholog Usp22 in the Glioblastoma Pseudo-Palisade Microlayer

KAT Gcn5 and DUB Ubp8 are required for respiration and mitochondria functions in budding yeast, and in this study we show that loss of respiratory activity is acquired over time. Interestingly, we show that absence of Ubp8 allows cells to grow in hypoxic conditions with altered mitophagy. Comparativ...

Descripción completa

Detalles Bibliográficos
Autores principales: De Luca, Veronica, Leo, Manuela, Cretella, Elisabetta, Montanari, Arianna, Saliola, Michele, Ciaffi, Gabriele, Vecchione, Andrea, Stoppacciaro, Antonella, Filetici, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140154/
https://www.ncbi.nlm.nih.gov/pubmed/35626719
http://dx.doi.org/10.3390/cells11101682