Ligustilide Inhibits Tumor Angiogenesis by Downregulating VEGFA Secretion from Cancer-Associated Fibroblasts in Prostate Cancer via TLR4

SIMPLE SUMMARY: Inhibiting the production of vascular endothelial growth factor A (VEGFA) can inhibit angiogenesis, thereby inhibiting tumor growth. We found that ligustilide can inhibit the secretion of VEGFA from prostate cancer-related fibroblasts (CAFs), and this signaling pathway is related to...

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Detalles Bibliográficos
Autores principales: Ma, Jing, Chen, Xu, Chen, Yumo, Tao, Ning, Qin, Zhihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140166/
https://www.ncbi.nlm.nih.gov/pubmed/35626012
http://dx.doi.org/10.3390/cancers14102406

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140166/
https://www.ncbi.nlm.nih.gov/pubmed/35626012
http://dx.doi.org/10.3390/cancers14102406

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