Interaction of Cationic Carbosilane Dendrimers and Their siRNA Complexes with MCF-7 Cells Cultured in 3D Spheroids

Cationic dendrimers are effective carriers for the delivery of siRNA into cells; they can penetrate cell membranes and protect nucleic acids against RNase degradation. Two types of dendrimers (CBD-1 and CBD-2) and their complexes with pro-apoptotic siRNA (Mcl-1 and Bcl-2) were tested on MCF-7 cells...

Descripción completa

Detalles Bibliográficos
Autores principales: Białkowska, Kamila, Komorowski, Piotr, Gomez-Ramirez, Rafael, de la Mata, Francisco Javier, Bryszewska, Maria, Miłowska, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140188/
https://www.ncbi.nlm.nih.gov/pubmed/35626734
http://dx.doi.org/10.3390/cells11101697

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140188/
https://www.ncbi.nlm.nih.gov/pubmed/35626734
http://dx.doi.org/10.3390/cells11101697

Ejemplares similares