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Interaction of Cationic Carbosilane Dendrimers and Their siRNA Complexes with MCF-7 Cells Cultured in 3D Spheroids

Cationic dendrimers are effective carriers for the delivery of siRNA into cells; they can penetrate cell membranes and protect nucleic acids against RNase degradation. Two types of dendrimers (CBD-1 and CBD-2) and their complexes with pro-apoptotic siRNA (Mcl-1 and Bcl-2) were tested on MCF-7 cells...

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Detalles Bibliográficos
Autores principales:	Białkowska, Kamila, Komorowski, Piotr, Gomez-Ramirez, Rafael, de la Mata, Francisco Javier, Bryszewska, Maria, Miłowska, Katarzyna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140188/ https://www.ncbi.nlm.nih.gov/pubmed/35626734 http://dx.doi.org/10.3390/cells11101697

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