Intellectual disability-associated disruption of O-GlcNAc cycling impairs habituation learning in Drosophila

O-GlcNAcylation is a reversible co-/post-translational modification involved in a multitude of cellular processes. The addition and removal of the O-GlcNAc modification is controlled by two conserved enzymes, O-GlcNAc transferase (OGT) and O-GlcNAc hydrolase (OGA). Mutations in OGT have recently bee...

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Detalles Bibliográficos
Autores principales: Fenckova, Michaela, Muha, Villo, Mariappa, Daniel, Catinozzi, Marica, Czajewski, Ignacy, Blok, Laura E. R., Ferenbach, Andrew T., Storkebaum, Erik, Schenck, Annette, van Aalten, Daan M. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140282/
https://www.ncbi.nlm.nih.gov/pubmed/35500025
http://dx.doi.org/10.1371/journal.pgen.1010159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140282/
https://www.ncbi.nlm.nih.gov/pubmed/35500025
http://dx.doi.org/10.1371/journal.pgen.1010159

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