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Tissue-Specific Variations in Transcription Factors Elucidate Complex Immune System Regulation

Gene expression plays a key role in health and disease. Estimating the genetic components underlying gene expression can thus help understand disease etiology. Polygenic models termed “transcriptome imputation” are used to estimate the genetic component of gene expression, but these models typically...

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Detalles Bibliográficos
Autores principales: Lu, Hengwei, Tang, Yi-Ching, Gottlieb, Assaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140347/
https://www.ncbi.nlm.nih.gov/pubmed/35627314
http://dx.doi.org/10.3390/genes13050929