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Potential Misidentification of Natural Isomers and Mass-Analogs of Modified Nucleosides by Liquid Chromatography–Triple Quadrupole Mass Spectrometry

Triple quadrupole mass spectrometry coupled to liquid chromatography (LC-TQ-MS) can detect and quantify modified nucleosides present in various types of RNA, and is being used increasingly in epitranscriptomics. However, due to the low resolution of TQ-MS and the structural complexity of the many na...

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Detalles Bibliográficos
Autores principales: Lin, Xiuying, Zhang, Qianhui, Qin, Yichao, Zhong, Qisheng, Lv, Daizhu, Wu, Xiaopeng, Fu, Pengcheng, Lin, Huan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140458/
https://www.ncbi.nlm.nih.gov/pubmed/35627263
http://dx.doi.org/10.3390/genes13050878