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Cannabidiol Enhances Microglial Beta-Amyloid Peptide Phagocytosis and Clearance via Vanilloid Family Type 2 Channel Activation

Alzheimer’s disease (AD) is associated with the accumulation and aggregation of amyloid in the brain. The cation channel TRPV2 may mediate the pathological changes in mild cognitive impairment. A high-affinity agonist of TRPV2 named cannabidiol is one of the candidate drugs for AD. However, the mole...

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Detalles Bibliográficos
Autores principales: Yang, Shaobin, Du, Yaqin, Zhao, Xiaoqian, Tang, Qi, Su, Wei, Hu, Yuemeng, Yu, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140666/
https://www.ncbi.nlm.nih.gov/pubmed/35628181
http://dx.doi.org/10.3390/ijms23105367