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Cannabidiol Enhances Microglial Beta-Amyloid Peptide Phagocytosis and Clearance via Vanilloid Family Type 2 Channel Activation
Alzheimer’s disease (AD) is associated with the accumulation and aggregation of amyloid in the brain. The cation channel TRPV2 may mediate the pathological changes in mild cognitive impairment. A high-affinity agonist of TRPV2 named cannabidiol is one of the candidate drugs for AD. However, the mole...
Autores principales: | Yang, Shaobin, Du, Yaqin, Zhao, Xiaoqian, Tang, Qi, Su, Wei, Hu, Yuemeng, Yu, Peng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140666/ https://www.ncbi.nlm.nih.gov/pubmed/35628181 http://dx.doi.org/10.3390/ijms23105367 |
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