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Light-Control over Casein Kinase 1δ Activity with Photopharmacology: A Clear Case for Arylazopyrazole-Based Inhibitors

Protein kinases are responsible for healthy cellular processes and signalling pathways, and their dysfunction is the basis of many pathologies. There are numerous small molecule inhibitors of protein kinases that systemically regulate dysfunctional signalling processes. However, attaining selectivit...

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Detalles Bibliográficos
Autores principales: Schulte, Albert M., Kolarski, Dušan, Sundaram, Vidya, Srivastava, Ashutosh, Tama, Florence, Feringa, Ben L., Szymanski, Wiktor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140716/
https://www.ncbi.nlm.nih.gov/pubmed/35628143
http://dx.doi.org/10.3390/ijms23105326