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STIM1–Orai1 Interaction Exacerbates LPS-Induced Inflammation and Endoplasmic Reticulum Stress in Bovine Hepatocytes through Store-Operated Calcium Entry

(1) Background: The basic mechanism of store-operated Ca(2+) entry (SOCE) in bovine hepatocytes (BHEC) is related to the activation of STIM1 and Orai1. The effect of STIM1- and Orai1-dependent calcium ion signaling on the NF-κB signaling pathway is unclear. (2) Methods: In this study, the expression...

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Detalles Bibliográficos
Autores principales: Xue, Yang, Zhou, Shendong, Xie, Wan, Meng, Meijuan, Ma, Nana, Zhang, Hongzhu, Wang, Yan, Chang, Guangjun, Shen, Xiangzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140735/
https://www.ncbi.nlm.nih.gov/pubmed/35627260
http://dx.doi.org/10.3390/genes13050874