The κ-Opioid Receptor Agonist U50488H Ameliorates Neuropathic Pain Through the Ca(2+)/CaMKII/CREB Pathway in Rats

OBJECTIVE: To observe the ameliorative effect of kappa opioid receptor (KOR) agonist on rats with neuropathic pain (NP) and investigate the mechanism of action of the calcium ion (Ca(2+))/calcium/calmodulin-dependent protein kinase II (CaMKII)/cyclic AMP response element-binding protein (CREB) pathw...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao-Min, Lun, Ming-Hui, Du, Wei, Ma, Fang, Huang, Ze-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140919/
https://www.ncbi.nlm.nih.gov/pubmed/35645576
http://dx.doi.org/10.2147/JIR.S327234

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140919/
https://www.ncbi.nlm.nih.gov/pubmed/35645576
http://dx.doi.org/10.2147/JIR.S327234

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