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The κ-Opioid Receptor Agonist U50488H Ameliorates Neuropathic Pain Through the Ca(2+)/CaMKII/CREB Pathway in Rats

OBJECTIVE: To observe the ameliorative effect of kappa opioid receptor (KOR) agonist on rats with neuropathic pain (NP) and investigate the mechanism of action of the calcium ion (Ca(2+))/calcium/calmodulin-dependent protein kinase II (CaMKII)/cyclic AMP response element-binding protein (CREB) pathw...

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Detalles Bibliográficos
Autores principales:	Zhang, Xiao-Min, Lun, Ming-Hui, Du, Wei, Ma, Fang, Huang, Ze-Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140919/ https://www.ncbi.nlm.nih.gov/pubmed/35645576 http://dx.doi.org/10.2147/JIR.S327234

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