The mechanisms of catalysis and ligand binding for the SARS-CoV-2 NSP3 macrodomain from neutron and x-ray diffraction at room temperature

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The nonstructural protein 3 (NSP3) macrodomain of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (Mac1) removes adenosine diphosphate (ADP) ribosylation posttranslational modifications, playing a key role in the immune evasion capabilities of the virus responsible for the coronavirus d...

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Detalles Bibliográficos
Autores principales: Correy, Galen J., Kneller, Daniel W., Phillips, Gwyndalyn, Pant, Swati, Russi, Silvia, Cohen, Aina E., Meigs, George, Holton, James M., Gahbauer, Stefan, Thompson, Michael C., Ashworth, Alan, Coates, Leighton, Kovalevsky, Andrey, Meilleur, Flora, Fraser, James S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140965/
https://www.ncbi.nlm.nih.gov/pubmed/35622909
http://dx.doi.org/10.1126/sciadv.abo5083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140965/
https://www.ncbi.nlm.nih.gov/pubmed/35622909
http://dx.doi.org/10.1126/sciadv.abo5083

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