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Specific Gain and Loss of Co-Expression Modules in Long-Lived Individuals Indicate a Role of circRNAs in Human Longevity

Deep RNA sequencing of 164 blood samples collected from long-lived families was performed to investigate the expression patterns of circular RNAs (circRNAs). Unlike that observed in previous studies, circRNA expression in long-lived elderly individuals (98.3 ± 3.4 year) did not exhibit an age-accumu...

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Detalles Bibliográficos
Autores principales: Ge, Ming-Xia, Jiang, Jian-Jun, Yang, Li-Qin, Yang, Xing-Li, He, Yong-Han, Li, Gong-Hua, Kong, Qing-Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9140997/
https://www.ncbi.nlm.nih.gov/pubmed/35627134
http://dx.doi.org/10.3390/genes13050749