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Age-Related DNA Methylation in Normal Kidney Tissue Identifies Epigenetic Cancer Risk Susceptibility Loci in the ANKRD34B and ZIC1 Genes

Both age-dependent and age-independent alteration of DNA methylation in human tissues are functionally associated with the development of many malignant and non-malignant human diseases. TCGA-KIRC data were biometrically analyzed to identify new loci with age-dependent DNA methylation that may contr...

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Detalles Bibliográficos
Autores principales: Serth, Jürgen, Peters, Inga, Hill, Bastian, Hübscher, Tatjana, Hennenlotter, Jörg, Klintschar, Michael, Kuczyk, Markus Antonius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141100/
https://www.ncbi.nlm.nih.gov/pubmed/35628134
http://dx.doi.org/10.3390/ijms23105327