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Age-Related DNA Methylation in Normal Kidney Tissue Identifies Epigenetic Cancer Risk Susceptibility Loci in the ANKRD34B and ZIC1 Genes
Both age-dependent and age-independent alteration of DNA methylation in human tissues are functionally associated with the development of many malignant and non-malignant human diseases. TCGA-KIRC data were biometrically analyzed to identify new loci with age-dependent DNA methylation that may contr...
Autores principales: | Serth, Jürgen, Peters, Inga, Hill, Bastian, Hübscher, Tatjana, Hennenlotter, Jörg, Klintschar, Michael, Kuczyk, Markus Antonius |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141100/ https://www.ncbi.nlm.nih.gov/pubmed/35628134 http://dx.doi.org/10.3390/ijms23105327 |
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