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Rare Variant Analysis and Molecular Dynamics Simulation in Alzheimer’s Disease Identifies Exonic Variants in FLG
Background: Although an increasing number of common variants contributing to Alzheimer’s disease (AD) are uncovered by genome-wide association studies, they can only explain less than half of the heritability of AD. Rare variant association studies (RVAS) has become an increasingly important area to...
Autores principales: | Xiong, Weixue, Cai, Jiahui, Li, Ruijia, Wen, Canhong, Tan, Haizhu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141140/ https://www.ncbi.nlm.nih.gov/pubmed/35627223 http://dx.doi.org/10.3390/genes13050838 |
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