Rare Variant Analysis and Molecular Dynamics Simulation in Alzheimer’s Disease Identifies Exonic Variants in FLG

Background: Although an increasing number of common variants contributing to Alzheimer’s disease (AD) are uncovered by genome-wide association studies, they can only explain less than half of the heritability of AD. Rare variant association studies (RVAS) has become an increasingly important area to...

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Detalles Bibliográficos
Autores principales: Xiong, Weixue, Cai, Jiahui, Li, Ruijia, Wen, Canhong, Tan, Haizhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141140/
https://www.ncbi.nlm.nih.gov/pubmed/35627223
http://dx.doi.org/10.3390/genes13050838

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141140/
https://www.ncbi.nlm.nih.gov/pubmed/35627223
http://dx.doi.org/10.3390/genes13050838

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