Design of Rational JAK3 Inhibitors Based on the Parent Core Structure of 1,7-Dihydro-Dipyrrolo [2,3-b:3′,2′-e] Pyridine

JAK3 differs from other JAK family members in terms of tissue distribution and functional properties, making it a promising target for autoimmune disease treatment. However, due to the high homology of these family members, targeting JAK3 selectively is difficult. As a result, exploiting small chang...

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Detalles Bibliográficos
Autores principales: Li, Yihao, Meng, Dan, Xie, Jiali, Li, Ruoyu, Wang, Zifan, Li, Jinlong, Mou, Lin, Deng, Xinhao, Deng, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141313/
https://www.ncbi.nlm.nih.gov/pubmed/35628248
http://dx.doi.org/10.3390/ijms23105437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141313/
https://www.ncbi.nlm.nih.gov/pubmed/35628248
http://dx.doi.org/10.3390/ijms23105437

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