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Reduction of BMPR2 mRNA Expression in Peripheral Blood of Pulmonary Arterial Hypertension Patients: A Marker for Disease Severity?

Pulmonary arterial hypertension (PAH) can be caused by pathogenic variants in the gene bone morphogenetic protein receptor 2 (BMPR2). While BMPR2 protein expression levels are known to be reduced in the lung tissue of heritable PAH (HPAH) patients, a systematic study evaluating expression in more ea...

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Detalles Bibliográficos
Autores principales: Theobald, Vivienne, Benjamin, Nicola, Seyfarth, Hans-Jürgen, Halank, Michael, Schneider, Marc A., Richtmann, Sarah, Hinderhofer, Katrin, Xanthouli, Panagiota, Egenlauf, Benjamin, Seeger, Rebekka, Hoeper, Marius M., Jonigk, Danny, Grünig, Ekkehard, Eichstaedt, Christina A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141548/
https://www.ncbi.nlm.nih.gov/pubmed/35627145
http://dx.doi.org/10.3390/genes13050759