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A New Zebrafish Model to Measure Neuronal α-Synuclein Clearance In Vivo

The accumulation and aggregation of α-synuclein (α-SYN) is a common characteristic of synucleinopathies, such as Parkinson’s Disease (PD), Dementia with Lewy Bodies (DLB) or Multiple System Atrophy (MSA). Multiplications of the wildtype gene of α-SYN (SNCA) and most point mutations make α-SYN more a...

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Detalles Bibliográficos
Autores principales: Lopez, Ana, Gorb, Alena, Palha, Nuno, Fleming, Angeleen, Rubinsztein, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141618/
https://www.ncbi.nlm.nih.gov/pubmed/35627253
http://dx.doi.org/10.3390/genes13050868