Non-Apoptotic Caspase-3 Activation Mediates Early Synaptic Dysfunction of Indirect Pathway Neurons in the Parkinsonian Striatum

Non-apoptotic caspase-3 activation is critically involved in dendritic spine loss and synaptic dysfunction in Alzheimer’s disease. It is, however, not known whether caspase-3 plays similar roles in other pathologies. Using a mouse model of clinically manifest Parkinson’s disease, we provide the firs...

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Detalles Bibliográficos
Autores principales: Fieblinger, Tim, Li, Chang, Espa, Elena, Cenci, M. Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141690/
https://www.ncbi.nlm.nih.gov/pubmed/35628278
http://dx.doi.org/10.3390/ijms23105470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141690/
https://www.ncbi.nlm.nih.gov/pubmed/35628278
http://dx.doi.org/10.3390/ijms23105470

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