Protein Prenyltransferases and Their Inhibitors: Structural and Functional Characterization

Protein prenylation is a post-translational modification controlling the localization, activity, and protein–protein interactions of small GTPases, including the Ras superfamily. This covalent attachment of either a farnesyl (15 carbon) or a geranylgeranyl (20 carbon) isoprenoid group is catalyzed b...

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Detalles Bibliográficos
Autores principales: Marchwicka, Aleksandra, Kamińska, Daria, Monirialamdari, Mohsen, Błażewska, Katarzyna M., Gendaszewska-Darmach, Edyta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141697/
https://www.ncbi.nlm.nih.gov/pubmed/35628237
http://dx.doi.org/10.3390/ijms23105424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141697/
https://www.ncbi.nlm.nih.gov/pubmed/35628237
http://dx.doi.org/10.3390/ijms23105424

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