Sepsis Encephalopathy Is Partly Mediated by miR370-3p-Induced Mitochondrial Injury but Attenuated by BAM15 in Cecal Ligation and Puncture Sepsis Male Mice

BAM15 (a mitochondrial uncoupling agent) was tested on cecal ligation and puncture (CLP) sepsis mice with in vitro experiments. BAM15 attenuated sepsis as indicated by survival, organ histology (kidneys and livers), spleen apoptosis (activated caspase 3), brain injury (SHIRPA score, serum s100β, ser...

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Detalles Bibliográficos
Autores principales: Hiengrach, Pratsanee, Visitchanakun, Peerapat, Tongchairawewat, Pakteema, Tangsirisatian, Ponphisudti, Jungteerapanich, Thitiphat, Ritprajak, Patcharee, Wannigama, Dhammika Leshan, Tangtanatakul, Pattarin, Leelahavanichkul, Asada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141734/
https://www.ncbi.nlm.nih.gov/pubmed/35628259
http://dx.doi.org/10.3390/ijms23105445

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141734/
https://www.ncbi.nlm.nih.gov/pubmed/35628259
http://dx.doi.org/10.3390/ijms23105445

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