Cargando…

Activation of Esterase D by FPD5 Inhibits Growth of A549 Lung Cancer Cells via JAB1/p53 Pathway

Esterase D (ESD) is widely distributed in mammals, and it plays an important role in drug metabolism, detoxification, and biomarkers and is closely related to the development of tumors. In our previous work, we found that a chemical small-molecule fluorescent pyrazoline derivative, FPD5, an ESD acti...

Descripción completa

Detalles Bibliográficos
Autores principales: Yao, Wen, Yang, Yuejun, Chen, Xinpeng, Cui, Xiaoling, Zhou, Bangzhao, Zhao, Baoxiang, Lin, Zhaomin, Miao, Junying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141839/
https://www.ncbi.nlm.nih.gov/pubmed/35627173
http://dx.doi.org/10.3390/genes13050786