Novel Benzoxazoles Containing 4-Amino-Butanamide Moiety Inhibited LPS-Induced Inflammation by Modulating IL-6 or IL-1β mRNA Expression

LPS induces inflammatory cytokines, including IL-1β, IL-6, and TNF-α, and causes an inflammatory response. The development of small molecules that have suppressive effect on those inflammatory cytokines is a desirable strategy for the treatment of inflammatory diseases. We synthesized 12 novel compo...

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Detalles Bibliográficos
Autores principales: Yoo, Jihye, Park, Jiyoung, Kim, Darong, Huh, Yeonjoo, Park Choo, Hea-Young, Woo, Hyun Ae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141988/
https://www.ncbi.nlm.nih.gov/pubmed/35628136
http://dx.doi.org/10.3390/ijms23105331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141988/
https://www.ncbi.nlm.nih.gov/pubmed/35628136
http://dx.doi.org/10.3390/ijms23105331

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