Topologically associating domains are disrupted by evolutionary genome rearrangements forming species-specific enhancer connections in mice and humans

Distinguishing between conserved and divergent regulatory mechanisms is essential for translating preclinical research from mice to humans, yet there is a lack of information about how evolutionary genome rearrangements affect the regulation of the immune response, a rapidly evolving system. The cur...

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Detalles Bibliográficos
Autores principales: Gilbertson, Sarah E., Walter, Hannah C., Gardner, Katherine, Wren, Spencer N., Vahedi, Golnaz, Weinmann, Amy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142060/
https://www.ncbi.nlm.nih.gov/pubmed/35508135
http://dx.doi.org/10.1016/j.celrep.2022.110769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142060/
https://www.ncbi.nlm.nih.gov/pubmed/35508135
http://dx.doi.org/10.1016/j.celrep.2022.110769

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