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Deciphering a hexameric protein complex with Angstrom optical resolution

Cryogenic optical localization in three dimensions (COLD) was recently shown to resolve up to four binding sites on a single protein. However, because COLD relies on intensity fluctuations that result from the blinking behavior of fluorophores, it is limited to cases where individual emitters show d...

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Detalles Bibliográficos
Autores principales: Mazal, Hisham, Wieser, Franz-Ferdinand, Sandoghdar, Vahid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142145/
https://www.ncbi.nlm.nih.gov/pubmed/35616526
http://dx.doi.org/10.7554/eLife.76308