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MSC-Derived Extracellular Vesicles Activate Mitophagy to Alleviate Renal Ischemia/Reperfusion Injury via the miR-223-3p/NLRP3 Axis

BACKGROUND: MSC-derived extracellular vehicles (EVs) exhibit a protective functional role in renal ischemia/reperfusion injury (RIRI). Recent studies have revealed that mitophagy could be a potential target process in the treatment of RIRI. However, whether MSC-derived EVs are involved in the regula...

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Detalles Bibliográficos
Autores principales: Sun, Zejia, Gao, Zihao, Wu, Jiyue, Zheng, Xiang, Jing, Shizhao, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142309/
https://www.ncbi.nlm.nih.gov/pubmed/35646124
http://dx.doi.org/10.1155/2022/6852661