In vivo impact of JAK3 A573V mutation revealed using zebrafish

BACKGROUND: Janus kinase 3 (JAK3) acts downstream of the interleukin-2 (IL-2) receptor family to play a pivotal role in the regulation of lymphoid cell development. Activating JAK3 mutations are associated with a number of lymphoid and other malignancies, with mutations within the regulatory pseudok...

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Detalles Bibliográficos
Autores principales: Basheer, Faiza, Bulleeraz, Vilasha, Ngo, Viet Q. T., Liongue, Clifford, Ward, Alister C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142468/
https://www.ncbi.nlm.nih.gov/pubmed/35622134
http://dx.doi.org/10.1007/s00018-022-04361-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142468/
https://www.ncbi.nlm.nih.gov/pubmed/35622134
http://dx.doi.org/10.1007/s00018-022-04361-8

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