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Toll-like receptor 9 deficiency induces osteoclastic bone loss via gut microbiota-associated systemic chronic inflammation

Toll-like receptors (TLRs) play pivotal roles in inflammation and provide important links between the immune and skeletal systems. Although the activation of TLRs may affect osteoclast differentiation and bone metabolism, whether and how TLRs are required for normal bone remodeling remains to be ful...

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Detalles Bibliográficos
Autores principales: Ding, Peng, Tan, Qiyuan, Wei, Zhanying, Chen, Qiyu, Wang, Chun, Qi, Luyue, Wen, Li, Zhang, Changqing, Yao, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142495/
https://www.ncbi.nlm.nih.gov/pubmed/35624094
http://dx.doi.org/10.1038/s41413-022-00210-3