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Toll-like receptor 9 deficiency induces osteoclastic bone loss via gut microbiota-associated systemic chronic inflammation
Toll-like receptors (TLRs) play pivotal roles in inflammation and provide important links between the immune and skeletal systems. Although the activation of TLRs may affect osteoclast differentiation and bone metabolism, whether and how TLRs are required for normal bone remodeling remains to be ful...
Autores principales: | Ding, Peng, Tan, Qiyuan, Wei, Zhanying, Chen, Qiyu, Wang, Chun, Qi, Luyue, Wen, Li, Zhang, Changqing, Yao, Chen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142495/ https://www.ncbi.nlm.nih.gov/pubmed/35624094 http://dx.doi.org/10.1038/s41413-022-00210-3 |
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