Polyploid giant cancer cells are dependent on cholesterol for progeny formation through amitotic division

Polyploid Giant Cancer Cells (PGCC) are increasingly being recognized as drivers of cancer recurrence. Therapy stress promotes the formation of these cells, which upon stress cessation often successfully generate more aggressive progeny that repopulate the tumor. Therefore, identification of potenti...

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Detalles Bibliográficos
Autores principales: White-Gilbertson, Shai, Lu, Ping, Esobi, Ikechukwu, Echesabal-Chen, Jing, Mulholland, Patrick J., Gooz, Monika, Ogretmen, Besim, Stamatikos, Alexis, Voelkel-Johnson, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142539/
https://www.ncbi.nlm.nih.gov/pubmed/35624221
http://dx.doi.org/10.1038/s41598-022-12705-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142539/
https://www.ncbi.nlm.nih.gov/pubmed/35624221
http://dx.doi.org/10.1038/s41598-022-12705-4

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