Stable G-quadruplex DNA structures promote replication-dependent genome instability

G-quadruplex (G4)–prone structures are abundant in mammalian genomes, where they have been shown to influence DNA replication, transcription, and genome stability. In this article, we constructed cells with a single ectopic homopurine/homopyrimidine repeat tract derived from the polycystic kidney di...

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Detalles Bibliográficos
Autores principales: Rider, S. Dean, Gadgil, Rujuta Yashodhan, Hitch, David C., Damewood, French J., Zavada, Nathen, Shanahan, Matilyn, Alhawach, Venicia, Shrestha, Resha, Shin-ya, Kazuo, Leffak, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142560/
https://www.ncbi.nlm.nih.gov/pubmed/35447109
http://dx.doi.org/10.1016/j.jbc.2022.101947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142560/
https://www.ncbi.nlm.nih.gov/pubmed/35447109
http://dx.doi.org/10.1016/j.jbc.2022.101947

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